* FTSEurofirst 300 index of top European shares down 0.5 pct
* More details on $700-billion U.S. bailout plan awaited
* Wall Street set for a weak start; European stocks fall
By Natsuko Waki
LONDON, Sept 22 (Reuters) - Wall Street is set to follow European stocks lower and the dollar fell on Monday as jittery investors awaited detail of Washington's $700 billion bailout to tackle the worst financial crisis since the Great Depression.
Global stocks posted the biggest one-day gain in 20 years on Friday after the U.S. Treasury proposed the largest-ever bank rescue plan and world authorities banned short selling and exercised other measures to restore calm in the markets.
However, many aspects of the U.S. plan have yet to be made public and concerns remained over the slowing U.S. economy and its impact on the rest of the world after a frantic week which saw the collapse of Lehman Brothers and the firesale of Merrill Lynch <MER.N> and UK bank HBOS <HBOS.L>.
"The plan dramatically reduces the systemic risks that have gripped the markets for a while," said Jacques Henry, analyst at Louis Capital Markets in Paris.
"The sharp stock rally we saw on Friday, by its magnitude, signals a big change in direction ... But we might not see a quick recovery because of the macroeconomic backdrop. The slowdown is real."
The FTSEurofirst 300 index <
> fell 0.5 percent while U.S. stock futures <SPc1> were down 0.6 percent, pointing to a weaker open on wall Street.Asia's 2.8-percent gain <.MIAPJ0000PUS> helped push MSCI main world equity index <.MIWD00000PUS> higher 0.7 percent, after rallying more than 6 percent on Friday -- its biggest percentage gain since at least 1988.
Shares of Goldman Sachs <GS.N> and Morgan Stanley <MS.N> fell in Europe after they became bank holdings companies regulated by the Federal Reserve, giving up their cherished investment banking status in return for cover under the central bank's wing.
"Even as the package is being debated, we could see more sizable losses or another significant institution come under pressure," said Richard McGuire, interest rate strategist at RBC Capital Markets.
West Virginia-based Ameribank became the 12th bank to collapse this year as the struggling economy and falling home prices take their toll on financial institutions.
END OF BEAR MARKET?
Friday's rally pushed the MSCI world equity index off last week's 2-1/2 year lows, bringing year-to-date losses to just under 20 percent.
"This cyclical bear market in risky assets is probably over, but whether a new bull market can be sustained is another matter. And despite the huge potential rise in U.S. government debt, the secular bull market in bonds probably still has a way to run," Credit Suisse said in a note to clients.
The dollar lost 0.5 percent against the euro to $1.4567 per euro <EUR=> and versus the low-yielding yen to 106.40 <JPY=>.
In the interbank market, tensions remained despite concerted action by the world's central banks to inject liquidity to the tune of hundreds of billions of dollars and Washington's $50 billion money market guarantee programme.
The premium on London interbank lending rates for three-month dollars <LIBOR> over the yield on risk-free U.S. Treasury paper <US3MT=RR> stood around 221 basis points.
The December Bund future <FGBLc1> fell 32 ticks as safe-haven flows dwindled.
Emerging sovereign spreads <11EMJ> tightened 4 basis points to trade 351 bps over U.S. Treasuries, while emerging stocks <.MSCIEF> rose 1.1 percent.
U.S. light crude <CLc1> rose 2.2 percent at $106.85 a barrel after rallying 7 percent on Friday. Gold <XAU=> rose to $880.15 an ounce.
(Additional reporting by Blaise Robinson, Naomi Tajitsu)