* FTSE 100 drops 2.1 pct by mid-session
* Banks lead losses after three days of strong gains
* Miners slide on lower metals prices, Xstrata rights issue
By Kylie MacLellan
LONDON, Jan 29 (Reuters) - Britain's leading index of shares fell 2.1 percent by mid-session on Thursday as banks retreated from a three-day rally, and miners were weighed down by lower metals prices and an Xstrata <XTA.L> rights issue plan.
By 1149 GMT the FTSE 100 <
> had fallen 90.04 points to trade at 4,205.16, having gained 2.4 percent on Wednesday. The index is down 5.2 percent so far this month having slid more than 31 percent last year -- its worst annual drop since its launch in 1984.UK banks were the biggest losers, as investors took stock after three days of hefty gains that have seen the sector rise 17.8 percent this week <.FTNMX8350>.
"It shouldn't be much of a surprise that we are down...I think people are just taking a little bit of profit," said Rob Griffiths, equity strategist at Cazenove.
Lloyds Banking Group <LLOY.L> led the fall, down 11.9 percent, having gained more than 50 percent on Wednesday as fears it would be nationalised faded.
"If you look at the prices of the banks we're pretty much exactly where we were two weeks ago so that (nationalisation) scare has in a sense passed and now we are back into normal territory," Griffiths added.
Barclays <BARC.L> was among the FTSE's top losers, down 9 percent, but at 97 pence was still well above the 47 pence it touched last week.
HSBC <HSBA.L>, Standard Chartered <STAN.L> and Royal Bank of Scotland <RBS.L> fell between 4.5 and 5.6 percent.
Private equity group 3i <III.L> tumbled 17.1 percent and touched a record low of 183 pence as investors continued to react negatively to Wednesday's news that the value of its investments had plunged in the last quarter.
MINERS DENTED
Miners were also among the biggest movers as the recent tumble in metals prices forced them to look at ways of raising capital.
Debt-laden miner Xstrata fell 9 percent after it said it is set to launch a $5.9 billion capital raising as it looks to reduce its debt burden in the wake of the global commodities slump. [
]"Mining stocks are quite heavily leveraged and on the basis that commodities have been under pressure recently it's perhaps not surprising the stock has been marked down on the back of that announcement," said Richard Hunter, head of equities at Hargreaves Lansdown.
Rio Tinto <RIO.L> fell 6.1 percent after newspaper reports said the miner is in talks with Chinalco [
], the Chinese state-owned metals group, about a capital injection and sale of assets.Other miners were also under pressure with copper, zinc and aluminium prices all down.
Anglo American <AAL.L>, Eurasian Natural Resources <ENRC.L> and Antofagasta <ANTO.L> fell between 3.1 and 5.2 percent.
Royal Dutch Shell <RDSa.L> gained 0.2 percent after it said its fourth quarter current cost of supply net profit fell 28 percent to $4.79 billion as crude prices collapsed but raised its dividend while lifting planned investments.
But other energy stocks retreated as crude prices slipped to around $41 per barrel <CLc1>. BP <BP.L>, Cairn Energy <CNE.L> and BG Group <BG.L> slid between 0.5 and 6.8 percent. Shares in pharmaceuticals giant AstraZeneca <AZN.L> slid 4.5 percent after it broadly met expectations, but traders said lack of sales growth forecast for the year dented sentiment.
British Sky Broadcasting <BSY.L> was one of a handful of companies in positive territory, up 2 percent after ratings agency S&P raised its price target and Goldman Sachs removed it from its pan-European conviction sell list.
Among midcaps <
>, industrial materials producer Cookson Group <CKSN.L> was the heaviest loser falling 15.3 percent after it announced a 240 million cash call and said it was cutting 1,250 jobs and scrapping its dividend in response to plunging steel markets. [ ]For a timeline on the British recession, click on: http://uk.reuters.com//news/globalcoverage/timelines/timeline?tx=20090128155121.xml&tn=The%20road%20to%20recession%20in%20Britain
(Editing by Elaine Hardcastle)