(Corrects first paragraph to show yen at 13-1/2-year high, not low, against dollar)
* Weak Microsoft, Nokia results hit U.S., European stocks
* Yen holds near 13-year peak vs dollar; sterling weak
* Geithner nears confirmation as U.S. Treasury Secretary
* Treasuries weaken on debt issuance fears, China remarks
By Steven C. Johnson
NEW YORK, Jan 22 (Reuters) - Wall Street swooned on Thursday after a surprisingly grim earnings report from Microsoft, following European shares lower, while anxious investors kept the yen near a 13-1/2-year peak against the U.S. dollar.
U.S. President Barack Obama's nominee to head the Treasury Department won approval from a Senate panel, clearing the way for a full Senate confirmation vote, and lifted the greenback when he said a strong dollar is in the U.S. national interest.
But U.S. government bond prices turned lower after Treasury Secretary designate Timothy Geithner said Obama believes China was manipulating its currency. China is the biggest holder of U.S. Treasuries, with some $682 billion as of November.
U.S. stocks fell after Microsoft <MSFT.O> said it would cut up to 5,000 jobs over 18 months and would not offer new profit forecasts for the rest of the fiscal year.
For full story see [
].Microsoft, the world's top software maker company, blamed its profit miss on weak personal computer sales, which undercut sales of its Windows operating system. Its shares fell more than 9 percent, bringing losses for the year to 40 percent.
"It is a negative surprise for the market, certainly from a bellwether technology company," said Richard Sparks, senior equities analyst at Schaeffer's Investment Research in Cincinnati, Ohio. "For Microsoft to miss its guidance, it brings home the pervasive fallout from the credit crisis."
The Dow Jones industrial average <
> was down 219.43 points, or 2.67 percent, at 8,008.67. The Standard & Poor's 500 Index <.SPX> was down 22.08 points, or 2.63 percent, at 818.16. The Nasdaq Composite Index < > was down 52.18 points, or 3.46 percent, at 1,454.89.Another batch of dismal U.S. economic data, this time on housing and unemployment, also weighed on share prices. [
]European shares also fell for a fourth straight day. The FTSEurofirst 300 <
> index of top European stocks fell 0.8 percent, led lower by a 9 percent slump in Nokia shares <NOK1V.HE> after the company reported disappointing earnings.U.S. crude oil <CLc1> prices fell $2.33, or 5.3 percent, to $41.24 per barrel.
GOVERNMENT DEBT CONCERNS
The dollar lost 0.6 percent to 88.87 yen <JPY=> after falling as low as 87.10 yen on Wednesday, the lowest since 1995.
The dollar rose against most other major currencies, with the euro dipping 0.4 percent to $1.2990 <EUR=> after Geithner reiterated support for a strong dollar. Sterling was down 0.7 percent at $1.3880 <GBP=> after fears about the UK banking sector on Wednesday drove it to its lowest level since 1985. The British currency has fallen around 6 percent this week.
Geithner's remarks on China, however, weighed on Treasury debt prices, pushing the benchmark 10-year note <US10YT=RR> down 20/32 in price, with the yield at 2.62 percent.
Expectations of a slew of U.S. debt issuance have been weighing on Treasury prices, and some investors worried that a the possibility of a tougher U.S. line on Chinese currency policy under Obama could prompt Beijing to purchase less debt.
"The Geithner comments on China coupled with the massive supply is weighing heavily on the long end of Treasuries," said Andrew Brenner, analyst at MF Global Inc in New York.
Sovereign debt worldwide has been under some pressure on concerns that governments will have to borrow huge amounts to help fund their packages designed to support the economy.
Worries about fiscal balance have driven the cost of insuring sovereign debt of many major economies to record highs in recent sessions, according to credit default swaps data.
Investors are also demanding more compensation to hold less liquid euro zone debt than benchmark German government bonds.
Spreads of French 10-year bonds over German Bunds are around 60 basis points, the widest since the euro's inception.
The 10-year Portuguese/Bund spread hit a new wide of 153 basis points on Wednesday after Portugal became the third euro zone economy this year to have its credit rating downgraded by Standard & Poor's. (Reporting by Reuters bureaus worldwide; Editing by James Dalgleish)