(Updates to Wall Street close)
* Weak Microsoft, Nokia results hit U.S., European stocks
* Yen holds near 13-year peak vs dollar; sterling weak
* Geithner confirmation vote timing unclear
* Treasuries weaken on debt issuance fears, China remarks
By Steven C. Johnson
NEW YORK, Jan 22 (Reuters) - Wall Street swooned on Thursday after a surprisingly grim earnings report from Microsoft, following European shares lower, while anxious investors kept the yen near a 13-1/2-year peak against the U.S. dollar.
U.S. President Barack Obama's nominee to head the Treasury Department, Timothy Geithner, won approval from a Senate panel, but it remained unclear how soon the full Senate would act on his confirmation, adding another element of anxiety.
The vote could come later on Thursday, but also could be pushed into next week if one or more Republicans object to a swift vote.
"We are basically leaderless in Treasury," said Tim Ghriskey, chief investment officer of Solaris Asset Management in Bedford Hills, New York. "It's an overhang right now and we need some leadership."
Even without his status confirmed, Geithner was a significant factor in financial markets. He lifted the dollar when he said a strong dollar is in the U.S. national interest, and sent U.S. government longer-dated bond prices lower after saying Obama believes China was manipulating its currency. China is the biggest holder of U.S. Treasuries, with some $682 billion as of November.
U.S. stocks fell after Microsoft <MSFT.O> said it would cut up to 5,000 jobs over 18 months and would not offer new profit forecasts for the rest of the fiscal year.
For full story see [
].Microsoft, the world's top software maker company, blamed weak personal computer sales, which undercut sales of its Windows operating system. Its shares fell 11.7 percent, its biggest one-day percentage loss in more than eight years.
"It is a negative surprise for the market, certainly from a bellwether technology company," said Richard Sparks, senior equities analyst at Schaeffer's Investment Research in Cincinnati, Ohio. "For Microsoft to miss its guidance, it brings home the pervasive fallout from the credit crisis."
The Dow Jones industrial average <
> closed down 105.3 points, or 1.3 percent, at 8,122.80. The Standard & Poor's 500 Index <.SPX> dropped 12.74 points, or 1.52 percent, to 827.50. The Nasdaq Composite Index < > ended lower by 41.58 points, or 2.76 percent, at 1,465.49.Another batch of dismal U.S. economic data, this time on housing and jobs, also weighed on shares. [
]European shares also fell for a fourth straight day. The FTSEurofirst 300 <
> index of top European stocks fell 0.8 percent, led lower by a 9 percent slump in Nokia shares <NOK1V.HE> after the company reported disappointing earnings.U.S. crude oil <CLc1> prices settled 12 cents higher at $43.67 per barrel, as optimism for an aggressive stimulus package from the Obama administration helped it claw back from steep losses earlier in the day that had been sparked by large stockpile increases in the latest week.
GOVERNMENT DEBT CONCERNS
The dollar lost 0.6 percent to 88.77 yen <JPY=> after falling to 87.10 yen on Wednesday, the lowest since 1995.
The dollar rose against most other major currencies, with the euro dipping 0.3 percent to $1.30 <EUR=> after Geithner reiterated support for a strong dollar. Sterling was down 0.76 percent at $1.3873 <GBP=> after fears about the UK banking sector on Wednesday drove it to its lowest level since 1985. The British currency has fallen around 6 percent this week.
Geithner's remarks on China, however, weighed on Treasury debt prices, pushing the benchmark 10-year note <US10YT=RR> down 14/32 in price, with the yield at 2.60 percent.
Expectations of a slew of U.S. debt issuance flooding the market have been weighing on Treasuries, and some investors worried the possibility of a tougher U.S. line on Chinese currency policy could prompt Beijing to purchase less debt.
"The Geithner comments on China coupled with the massive supply is weighing heavily on the long end of Treasuries," said Andrew Brenner, analyst at MF Global Inc in New York.
Sovereign debt worldwide has been under some pressure on concerns that governments will have to borrow huge amounts to help fund packages designed to support their economy.
Worries about fiscal balance have driven the cost of insuring sovereign debt of many major economies to record highs in recent sessions, according to credit default swaps data.
Investors are also demanding more compensation to hold less liquid euro zone debt than benchmark German government bonds.
Spreads of French 10-year bonds over German Bunds are around 60 basis points, the widest since the euro's inception. (Reporting by Reuters bureaus worldwide; Editing by Chizu Nomiyama)