* Wall Street lower on weak Cisco results, outlook
* U.S. weekly jobless claims drop to 2-1/2 year low
* U.S. dollar rallies on jobless claims report
* Portugal debt concerns weigh on euro
By Daniel Bases
NEW YORK, Feb 10 (Reuters) - Weak corporate results jeopardized an eight-day rally in the Dow industrials and weighed on European stocks on Thursday, overshadowing upbeat weekly U.S. jobless claims data that boosted the U.S. dollar.
A stronger greenback has put some selling pressure on commodity prices. The dollar gained after the U.S. Labor Department reported an unexpected drop in initial claims for unemployment benefits to their lowest level in 2-1/2 years.
"(Claims) looked good and the market had a muted but positive reaction to them," said Tim Ghriskey, chief investment officer at Solaris Asset Management in Bedford Hills, New York.
"It comes at a time of year where earnings are being reported and it looks like, at least this morning, we are going to see a bit of profit taking in the market," he said.
After weeks of generally positive news on the corporate front that has lifted benchmark indexes to 2-1/2 year highs, investors have suddenly been presented with a barrage of less than robust reports.
The latest reading of U.S. earnings, for instance, showed that of the companies listed on the Standard & Poor's 500 index, 72 percent of those reporting have beaten analysts' mean quarterly estimates, according to Thomson Reuters data.
However, companies such as computer networking equipment maker Cisco Systems Inc <CSCO.O> fell 11.75 percent to $19.45 a day after warning about dwindling public spending and weaker margins.
In Europe, major bank Credit Suisse <CSGN.VX> missed profit expectations because of debt charges, and Diageo <DGE.L>, the world's biggest spirits group, missed expectations with just a 9 percent rise in half-year earnings.
The Dow Jones industrial average <
> fell 64.64 points, or 0.53 percent, to 12,175.25. The Standard & Poor's 500 Index <.SPX> lost 7.06 points, or 0.53 percent, to 1,313.82. The Nasdaq Composite Index < > was down 9.88 points, or 0.35 percent, at 2,779.19.MSCI's all-country world index <.MIWD00000PUS> fell 1.09 percent, pressured in particular by emerging markets. The EM sub-index lost 1.89 percent.
Europe's FTSEurofirst 300 <
> was off 0.6 percent, even with a gain of 2.59 percent for Deutsche Boerse <DB1Gn.DE>, which looks set to buy peer NYSE Euronext <NYX.N>. NYSE'S stock fell 2.36 percent in early New York trading.Japan's Nikkei closed down 0.1 percent.
Most developed markets remain in the black for the year however, with U.S. indexes leading the way, reflecting a shift this year from emerging markets to developed ones.
DOLLAR SURGE
The U.S. dollar's rise accelerated after the weekly jobless claims report showed a drop to a seasonally adjusted 383,000, the lowest since July 2008.
While the U.S. data underpinned the greenback's gains, investors remain worried about Europe's lack of progress in tackling a sovereign debt crisis which undermined the euro.
"I think this can continue as the run-up in yields is dollar-supportive and now we're encountering a renewed sense of fear about euro zone debt issues," said Brian Dolan, chief strategist at Forex.com in Bedminster, New Jersey.
The euro, which hit a 12-week high above $1.38 earlier this month, struggled as investors drove Portuguese bond yields to their highest level since the currency was introduced in 1999.
Portugal is considered at risk of becoming the next euro zone country to need a bailout. The European Central Bank stepped in to buy Portuguese bonds to help stabilize the fragile market.
The euro fell 1.05 percent to $1.3586 <EUR=> while sterling dropped 0.45 percent to $1.6031 percent <GPB=>.
Sterling fell after the Bank of England left interest rates at a record low. Traders said a recent spike in U.S. yields set the dollar up for further near-term gains.
The dollar made 1 percent gains against the Swiss franc, rising to 0.9670 francs <CHF=> and rose 0.96 percent against the yen to 83.15 <JPY=>.
U.S. Treasury debt prices fell, renewing their recent selloff, as traders sold older issues to make room for $16 billion in 30-year bonds in this week's quarterly refunding.
U.S. light sweet crude oil <CLc1> rose 87 cents, or 1 percent, to $87.58 per barrel. Spot gold prices <XAU=> fell $7.54, or 0.55 percent, to $1354.80. (Additional reporting by Jeremy Gaunt, William James, Richard Leong, Rodrigo Campos, Steven C. Johnson, Neal Armstrong and Brian Gorman; Editing by Kenneth Barry)